N-ACETYLOXINDOLE 97
N-Acetyl-2-oxindole
CAS: 21905-78-2
Molecular Formula: C10H9NO2
N-ACETYLOXINDOLE 97 - Names and Identifiers
| Name | N-Acetyl-2-oxindole |
| Synonyms | 100735 Nsc286428 1-Acetyloxindole 1-Acetyloxindole N-Acetyl-2-oxindole N-ACETYLOXINDOLE 97 2-Indolinone, 1-acetyl- 1-acetyl-1,3-dihydro-2H-indol-2-one 2H-Indol-2-one, 1-acetyl-1,3-dihydro- N-Acetyl-2-oxindole in stock Factory |
| CAS | 21905-78-2 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C10H9NO2/c1-7(12)11-9-5-3-2-4-8(9)6-10(11)13/h2-5H,6H2,1H3 |
N-ACETYLOXINDOLE 97 - Physico-chemical Properties
| Molecular Formula | C10H9NO2 |
| Molar Mass | 175.18 |
| Density | 1.275±0.06 g/cm3(Predicted) |
| Melting Point | 127-131°C(lit.) |
| Boling Point | 399.8±31.0 °C(Predicted) |
| Flash Point | 203.5°C |
| Vapor Presure | 1.33E-06mmHg at 25°C |
| pKa | -0.58±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.595 |
N-ACETYLOXINDOLE 97 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
N-ACETYLOXINDOLE 97 - Introduction
N-Acetyl-2-oxindole (N-Acetyl-2-oxindole) is an organic compound with the chemical formula C10H9NO2.
Nature:
N-Acetyl-2-oxindole is a white or light yellow crystal. It has an aromatic odor and is soluble in organic solvents such as ethanol, chloroform and acetic acid. Its melting point is 90-92 ° C.
Use:
N-Acetyl-2-oxindole has important application value in organic synthesis. It can be used as an intermediate for the synthesis of various compounds, such as natural products or drug precursors, as well as synthetic raw materials for dyes, fungicides and antioxidants. In addition, N-Acetyl-2-oxindole can also be used for drug research.
Method:
N-Acetyl-2-oxindole can be obtained by reacting indolinone with acetic anhydride. Specifically, indolinone is reacted with acetic anhydride under an alkaline condition, and the reaction mixture is heated and then subjected to an acidification treatment to finally obtain a product.
Safety Information:
There is little data on the safety of N-Acetyl-2-oxindole. As a chemical substance, use should follow laboratory safety procedures and take appropriate personal protective measures, such as wearing protective glasses and gloves. In addition, it should be stored in a dry, well-ventilated place, and avoid contact with strong oxidants and strong acids. If ingested or inhaled, seek medical attention immediately.
Nature:
N-Acetyl-2-oxindole is a white or light yellow crystal. It has an aromatic odor and is soluble in organic solvents such as ethanol, chloroform and acetic acid. Its melting point is 90-92 ° C.
Use:
N-Acetyl-2-oxindole has important application value in organic synthesis. It can be used as an intermediate for the synthesis of various compounds, such as natural products or drug precursors, as well as synthetic raw materials for dyes, fungicides and antioxidants. In addition, N-Acetyl-2-oxindole can also be used for drug research.
Method:
N-Acetyl-2-oxindole can be obtained by reacting indolinone with acetic anhydride. Specifically, indolinone is reacted with acetic anhydride under an alkaline condition, and the reaction mixture is heated and then subjected to an acidification treatment to finally obtain a product.
Safety Information:
There is little data on the safety of N-Acetyl-2-oxindole. As a chemical substance, use should follow laboratory safety procedures and take appropriate personal protective measures, such as wearing protective glasses and gloves. In addition, it should be stored in a dry, well-ventilated place, and avoid contact with strong oxidants and strong acids. If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-09 21:54:55
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View History
N-ACETYLOXINDOLE 97
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